естественные науки

медицина / здравоохранение

математика

электроника

клиническая медицина

Methods and Applications of Statistics in Clinical Trials, Volume 2: Planning, Analysis, and Inferential Methods includes updates of established literature from the Wiley Encyclopedia of Clinical Trials as well as original material based on the latest developments in clinical trials. Prepared by a leading expert, the second volume includes numerous contributions from current prominent experts in the field of medical research. In addition, the volume features: • Multiple new articles exploring emerging topics, such as evaluation methods with threshold, empirical likelihood methods, nonparametric ROC analysis, over- and under-dispersed models, and multi-armed bandit problems • Up-to-date research on the Cox proportional hazard model, frailty models, trial reports, intrarater reliability, conditional power, and the kappa index • Key qualitative issues including cost-effectiveness analysis, publication bias, and regulatory issues, which are crucial to the planning and data management of clinical trials


документальная литература

Methods and Applications of Statistics in Clinical Trials, Volume 2. Planning, Analysis, and Inferential Methods

A complete guide to the key statistical concepts essential for the design and construction of clinical trials As the newest major resource in the field of medical research, Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs presents a timely and authoritative reviewof the central statistical concepts used to build clinical trials that obtain the best results. The referenceunveils modern approaches vital to understanding, creating, and evaluating data obtained throughoutthe various stages of clinical trial design and analysis. Accessible and comprehensive, the first volume in a two-part set includes newly-written articles as well as established literature from the Wiley Encyclopedia of Clinical Trials. Illustrating a variety of statistical concepts and principles such as longitudinal data, missing data, covariates, biased-coin randomization, repeated measurements, and simple randomization, the book also provides in-depth coverage of the various trial designs found within phase I-IV trials. Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs also features: Detailed chapters on the type of trial designs, such as adaptive, crossover, group-randomized, multicenter, non-inferiority, non-randomized, open-labeled, preference, prevention, and superiority trials Over 100 contributions from leading academics, researchers, and practitioners An exploration of ongoing, cutting-edge clinical trials on early cancer and heart disease, mother-to-child human immunodeficiency virus transmission trials, and the AIDS Clinical Trials Group Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs is an excellent reference for researchers, practitioners, and students in the fields of clinicaltrials, pharmaceutics, biostatistics, medical research design, biology, biomedicine, epidemiology,and public health.


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Methods and Applications of Statistics in Clinical Trials, Volume 1. Concepts, Principles, Trials, and Designs

This book provides the basics needed to develop sensor network software and supplements it with many case studies covering network applications. It also examines how to develop onboard applications on individual sensors, how to interconnect these sensors, and how to form networks of sensors, although the major aim of this book is to provide foundational principles of developing sensor networking software and critically examine sensor network applications. 


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современная зарубежная литература

Fundamentals of Sensor Network Programming. Applications and Technology

Expert practical and theoretical coverage of runs and scans This volume presents both theoretical and applied aspects of runs and scans, and illustrates their important role in reliability analysis through various applications from science and engineering. Runs and Scans with Applications presents new and exciting content in a systematic and cohesive way in a single comprehensive volume, complete with relevant approximations and explanations of some limit theorems. The authors provide detailed discussions of both classical and current problems, such as: * Sooner and later waiting time * Consecutive systems * Start-up demonstration testing in life-testing experiments * Learning and memory models * «Match» in genetic codes Runs and Scans with Applications offers broad coverage of the subject in the context of reliability and life-testing settings and serves as an authoritative reference for students and professionals alike.

публицистическая литература

культура и искусство

статьи

русская классика

публицистика

критика

Runs and Scans with Applications

The first and only comprehensive guide to modern record theory and its applications Although it is often thought of as a special topic in order statistics, records form a unique area, independent of the study of sample extremes. Interest in records has increased steadily over the years since Chandler formulated the theory of records in 1952. Numerous applications of them have been developed in such far-flung fields as meteorology, sports analysis, hydrology, and stock market analysis, to name just a few. And the literature on the subject currently comprises papers and journal articles numbering in the hundreds. Which is why it is so nice to have this book devoted exclusively to this lively area of statistics. Written by an exceptionally well-qualified author team, Records presents a comprehensive treatment of record theory and its applications in a variety of disciplines. With the help of a multitude of fascinating examples, Professors Arnold, Balakrishnan, and Nagaraja help readers quickly master basic and advanced record value concepts and procedures, from the classical record value model to random and multivariate record models. The book follows a rational textbook format, featuring witty and insightful chapter introductions that help smooth transitions from one topic to another and challenging chapter-end exercises, which expand on the material covered. An extensive bibliography and numerous references throughout the text specify sources for further readings on relevant topics. Records is a valuable professional resource for probabilists and statisticians, in addition to applied statisticians, meteorologists, hydrologists, market analysts, and sports analysts. It also makes an excellent primary text for courses in record theory and a supplement to order statistics courses.

Records

Continuous Multivariate Distributions, Volume 1, Second Edition provides a remarkably comprehensive, self-contained resource for this critical statistical area. It covers all significant advances that have occurred in the field over the past quarter century in the theory, methodology, inferential procedures, computational and simulational aspects, and applications of continuous multivariate distributions. In-depth coverage includes MV systems of distributions, MV normal, MV exponential, MV extreme value, MV beta, MV gamma, MV logistic, MV Liouville, and MV Pareto distributions, as well as MV natural exponential families, which have grown immensely since the 1970s. Each distribution is presented in its own chapter along with descriptions of real-world applications gleaned from the current literature on continuous multivariate distributions and their applications.

N. Balakrishnan