The same careful rigour imposed on the design of phase III randomised controlled trials is not always applied to medical research in other areas such as trials conducted at earlier stages of drug development. With the emphasis that is now placed on evidence-based medicine, such care and rigour will inevitably impact on these areas with increasing attention turned to the quality of design. This title describes what principles can be used to structure research effectively allowing for the required degree of accuracy. Written by two best selling authors, this book includes many examples from medical literature and will be of great value to all groups conducting studies at the interface of clinical and laboratory research.

медицина / здравоохранение

клиническая медицина

медицина

The Design of Studies for Medical Research

Quality of Life. The Assessment, Analysis and Reporting of Patient-reported Outcomes

Quality of Life

Textbook of Clinical Trials

An Introduction to Statistics in Early Phase Trials

Sample Size Tables for Clinical Studies

Statistics with Confidence

Survival Analysis

Randomised Clinical Trials