Edited by two experts working at the pioneering pharmaceutical company and major global player in hormone-derived drugs, this handbook and reference systematically treats the drug development aspects of all human nuclear receptors, including recently characterized receptors such as PPAR, FXR and LXR. Authors from leading pharmaceutical companies around the world present examples and real-life data from their own work.

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фармакология

медицина

Nuclear Receptors as Drug Targets

Animal Models for Human Cancer. Discovery and Development of Novel Therapeutics

Fragment-based Drug Discovery. Lessons and Outlook

Pharmacokinetics and Metabolism in Drug Design

In vivo Models for Drug Discovery

Reactive Drug Metabolites

Scaffold Hopping in Medicinal Chemistry

Data Mining in Drug Discovery

Drug Metabolism Prediction