The mapping of human genes is proceeding rapidly. Genes associated with specific inherited diseases are being identified, often providing insight into the molecular cause of the disease. At the moment, however, little consideration is being given to the variation present in different human populations. Variation in the Human Genome discusses methods of analysing population genetic data and how contemporary genetic heterogeneity arises during the evolution and migration of human populations. Specific disorders such as cystic fibrosis, beta-thalassaemia, fragile X, phenylketonuria and tumour development susceptibility are used to illustrate this genetic variability and mechanisms of gene mutation and evolution.

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научно-популярная литература

зарубежная образовательная литература

знания и навыки

Variation in the Human Genome

The Biology of Extracellular Molecular Chaperones

Gramicidin and Related Ion Channel-Forming Peptides

Signalling Pathways in Acute Oxygen Sensing

The Molecular Biology and Pathology of Elastic Tissues

Oligonucleotides as Therapeutic Agents

Acetaldehyde-Related Pathology

Role of the Sarcoplasmic Reticulum in Smooth Muscle

IgE, Mast Cells and the Allergic Response