Innovative approach to drug design that's more likely to result in an approvable drug product Retrometabolic drug design incorporates two distinct drug design approaches to obtain soft drugs and chemical delivery systems, respectively. Combining fundamentals with practical step-by-step examples, Retrometabolic Drug Design and Targeting gives readers the tools they need to take full advantage of re…
Genomic Applications for Crop Breeding: Biotic Stress is the first of two volumes looking at the latest advances in genomic applications to crop breeding. This volume focuses on genomic-assisted advances for improving economically important crops against biotic stressors, such as viruses, fungi, nematodes, and bacteria. Looking at key advances in crops such as rice, barley, wheat, and potato among…
Demonstrates the advantages of catalytic cascade reactions for synthesizing natural products and pharmaceuticals Riding the wave of green chemistry, catalytic cascade reactions have become one of the most active research areas in organic synthesis. During a cascade reaction, just one reaction solvent, one workup procedure, and one purification step are needed, thus significantly increasing synthet…
Taking a refreshingly different approach to the subject, this new textbook uses original case studies of psychological support work with individual athletes and groups to illustrate the underlying theory and inform the reader of cutting edge practice in the field. It addresses ‘real world’ issues and helps the student understand the problems and challenges that the sport psychologist faces and is …
Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 8th Edition is the comprehensive revision of the field-leading reference on bone and mineral health. The eighth edition has been fully revised by the leading researchers and clinicians in the field to provide concise coverage of the widest possible spectrum of metabolic bone diseases and disorders of mineral metabolism. Cha…
SOON TO BE A MAJOR MOTION PICTURED DIRECTED BY AND STARRING CHIWETEL EJIOFOR.When William Kamkwamba was just 14 years old, his family told him that he must leave school and come home to work on the farm – they could no longer afford his fees. This is his story of how he found a way to make a difference, how he bought light to his family and village, and hope to his nation.Malawi is a country battl…
Chasing the Moon thoroughly reimagines the race to the moon, upending much of the conventional mythology. With newly revealed stories about the moon race, from its earliest days to the monumental achievement of the lunar landing in 1969, the book features a diverse cast of characters who played key roles in these historic events.Utilising a wealth of previously overlooked and lost archival materia…
‘Fascinating … so enlightening that suddenly maths doesn’t seem so fearsome as it once did’ SIMON WINCHESTERFrom Aristotle to Ada Lovelace: a brief history of the mathematical ideas that have forever changed the world and the everyday people and pioneers behind them. The story of our best invention yet.From our ability to calculate the passing of time to the algorithms that control computers and m…
A’ NO LOGO’ for the net Generation – a no-holes barred story of the battle for the control of the internet, that reads like a thriller.In November 1999, at the height of the e-commerce gold rush, an extraordinary hearing took place in a Los Angeles courtroom. On one side, the billion-dollar darling of Wall Street, eToys.com, the brain child of Toby Lenk, one of the hottest entrepreneurs of his gen…
In a world where we're bombarded with advice on going green, authors Mark Townsend and David Glick take a refreshing line and tell us how NOT to go green. Indeed, they're here to help us f**k up the planet good and proper. And it's easier than you think.An irreverent celebration of environmental doom and gloom, 50 Ways to F**k the Planet takes the 'eco-handbook' in an outrageous new direction, exp…
206 bones. One heart. Two eyes. Ten fingers. You may think we know what makes up a human. But it turns out our bodies are full of surprises.What makes tears of joy different from tears of sadness?Why is a gut feeling so much smarter than you think?And why is 90% of you not even human?You may think you know the human body – heart, lungs, brain and bones – but it’s time to think again. Your body is …
This richly illustrated hands-on guide is designed for researchers, teachers and practitioners. The huge selection of examples taken from science, basic teaching of physics, practical applications in industry and a variety of other disciplines spanning the range from medicine to volcano research allows readers to pick those that come closest to their own individual task at hand. Following a look a…
A rigorous mathematical problem-solving framework for analyzing the Earth’s energy resources GeoEnergy encompasses the range of energy technologies and sources that interact with the geological subsurface. Fossil fuel availability studies have historically lacked concise modeling, tending instead toward heuristics and overly-complex processes. Mathematical GeoEnergy: Oil Discovery, Depletion and R…
Geological Carbon Storage Subsurface Seals and Caprock Integrity Seals and caprocks are an essential component of subsurface hydrogeological systems, guiding the movement and entrapment of hydrocarbon and other fluids. Geological Carbon Storage: Subsurface Seals and Caprock Integrity offers a survey of the wealth of recent scientific work on caprock integrity with a focus on the geological control…
Provides an excellent balance between theory and applications in the ever-evolving field of water and wastewater treatment Completely updated and expanded, this is the most current and comprehensive textbook available for the areas of water and wastewater treatment, covering the broad spectrum of technologies used in practice today—ranging from commonly used standards to the latest state of the ar…