This practice-oriented handbook surveys current knowledge on the prediction and prevention of adverse drug reactions related to off-target activity of small molecule drugs. It is unique in collating the current approaches into a single source, and includes several highly instructive case studies that may be used as guidelines on how to improve drug development projects. With its large section on A…
A Companion to Economic Geography presents students of human geography with an essential collection of original essays providing a key to understanding this important subdiscipline. The contributions are written by prominent international scholars offering a wide-ranging overview of the field. Places economic geography in the wider context of geography. Contributions from leading international sch…
This first book to critically summarize the latest achievements and emerging applications within this interdisciplinary topic focuses on one of the most important types of detectors for elementary particles and photons: resistive plate chambers (RPCs). In the first part, the outstanding, international team of authors comprehensively describes and presents the features and design of single and doub…
Bioinformatics, in this context the application of computer science to biological problems, has become an indispensable part of any research in the biosciences. Rapid developments in gene sequencing, structure determination as well as rational protein engineering and design have made it necessary for biologists, chemists, and computer scientists to channel their expertise into large scale collabor…
Progress in Physical Organic Chemistry is dedicated to reviewing the latest investigations into organic chemistry that use quantitative and mathematical methods. These reviews help readers understand the importance of individual discoveries and what they mean to the field as a whole. Moreover, the authors, leading experts in their fields, offer unique and thought-provoking perspectives on the curr…
Whilst there is now overwhelming evidence that greenhouse-gas pollution is becoming the dominant process responsible for global warming, it is also clear that the climate system varies quite naturally on different time-scales. Predicting the course of future climate change consequently requires an understanding of the natural variability of the climate system as well as the effects of human-induce…
Homogeneous asymmetric catalysis offers reliable results and the possibility to 'tune' the catalysis on a rational basis. A pitfall, however, is that the separation of the catalyst from the starting material and products is difficult and often results in the loss of the catalytic material. Immobilization offers a potential solution for the user of enantioselective catalysts in industrial processes…
* Explains the physical meaning of linear and nonlinear structural mechanics. * Shows how to perform nonlinear structural analysis. * Points out important nonlinear structural dynamics behaviors. * Provides ready-to-use governing equations.
Brings together the latest research in the cellular and molecular biology of bones and teeth, including applications to medical and dental practice. An interdisciplinary group of contributors addresses control of bone formation, resorption and remodelling, osteoblast differentiation and osteoclast activity, factors influencing dental extracellular matrix biomineralization, non-collagen proteins in…
A complete survey of modern design and analysis techniques for optical waveguides This volume thoroughly details modern and widely accepted methods for designing the optical waveguides used in telecommunications systems. It offers a straightforward presentation of the sophisticated techniques used in waveguide analysis and enables a quick grasp of modern numerical methods with easy mathematics. Th…
Comprised of essays by top scholars in the field, this volume offers detailed overviews of philosophical issues raised by biology. Brings together a team of eminent scholars to explore the philosophical issues raised by biology Addresses traditional and emerging topics, spanning molecular biology and genetics, evolution, developmental biology, immunology, ecology, mind and behaviour, neuroscience,…
Crime Mapping Case Studies: From Research to Practice provides a series of key examples from practice and research that demonstrate applications of crime mapping and its effect in many areas of policing and crime reduction. This book brings together case studies that show how crime mapping can be used for analysis, intelligence development, monitoring performance, and crime detection and is writte…
Introduction to Magnetic Materials, 2nd Edition covers the basics of magnetic quantities, magnetic devices, and materials used in practice. While retaining much of the original, this revision now covers SQUID and alternating gradient magnetometers, magnetic force microscope, Kerr effect, amorphous alloys, rare-earth magnets, SI Units alongside cgs units, and other up-to-date topics. In addition, t…
This book describes the electrochemical behavior of supramolecular systems. Special emphasis will be given to the electrochemistry of host-guest complexes, monolayer and multilayer assemblies, dendrimers, and other supramolecular assemblies. A fundamental theme throughout the book is to explore the effects that supramolecular structure exerts on the thermodynamics and kinetics of electrochemical r…
From the utilization of textile waste to the high-tech product – this is how modern nonwovens can best described. Web formation and web bonding processes have recently being enhanced. Nowadays, fibres, granulates, binder and finishing agents are used. This development entails a wider range of applications in the fields of hygiene, medicine, the garment-producing and building industries, interior d…