Critical Care Nursing: Learning from Practice takes a unique approach to critical care. Based around case scenarios that have the patient as the central focus, each chapter is constructed around an example of a critically ill patient with specific care needs. The chapters then go on to critically explore the knowledge and skills required to deliver expert care. This book looks at a range of critic…
A new addition to the Neurology in Practice series, Neuromuscular Disorders provides a clinical guide to the challenging diagnosis and management of neuromuscular disorders. As a part of the series, various feature boxes are highlighted throughout. «Tips and Tricks» give suggestions on how to improve outcomes through practical technique or patient questioning. In addition, «Caution» warning boxes …
New and emerging directions in pharmaceutical research to better treat schizophrenia Although the dopamine hypothesis has been the cornerstone of schizophrenia therapeutics, it is clear that dopamine-based approaches do not treat all aspects of the disease. Moreover, many schizophrenia patients fail to respond to current antipsychotics. Integrating chemistry, biology, and pharmacology, this book e…
Over the past two decades the benefits of label-free biosensor analysis have begun to make an impact in the market, and systems are beginning to be used as mainstream research tools in many drug discovery laboratories. Label-Free Technologies For Drug Discovery summarises the latest and emerging developments in label-free detection systems, their underlying technology principles and end-user case …
Fundamentals of Light Microscopy and Electronic Imaging, Second Edition provides a coherent introduction to the principles and applications of the integrated optical microscope system, covering both theoretical and practical considerations. It expands and updates discussions of multi-spectral imaging, intensified digital cameras, signal colocalization, and uses of objectives, and offers guidance i…
As neuroimaging becomes more widespread, it is increasingly being used in the courts, even though understanding and interpreting neuroimaging methods and results can be very challenging – even without attempting to evaluate their potential applications to forensic questions. The sheer volume of available information, research results, and opinions can seem intimidating to forensic practitioners an…
Focusing exclusively on the surgical management of aortic arch disease in adults, this concise reference provides authoritative guidance on both standard and alternative approaches from internationally recognized experts. Topics include: general principles of aortic diseases imaging techniques intraoperative management neurologic protection strategies options for aortic repair surgical treatment o…
A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviews the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover…
Advances in Small Animal Total Joint Replacement provides an up-to-date, comprehensive examination of joint replacement in veterinary surgery. Part of the Advances in Veterinary Surgery series copublished with the ACVS Foundation, the book presents an evidence-based, multi-system examination of the current state of hip, knee, and elbow replacement in dogs and cats, including information on biomech…
This third volume in the successful 'Drug Discovery in Infectious Diseases' series is the first to deal with drug discovery in helminthic infections in human and animals. The result is a broad overview of different drug target evaluation methods, including specific examples of successful drug development against helminthes, and with a whole section devoted to vaccine development. With its well-bal…
The field of oncology benefits from several large-scale reference books and a host of monographs dedicated to specific cancers. However, truly excellent practice and review books are, surprisingly, quite scarce. Outside of a scant handful of books and online reference tools that offer clinical response practice and board review in a basic question and answer format, there are no resources that off…
A state-of-the-art, multidisciplinary approach to cancer and aging With the majority of cancers occurring in individuals over the age of 65 against a backdrop of an expanding aging population, there is an urgent need to integrate the areas of clinical oncology and geriatric care. This timely work tackles these issues head-on, presenting a truly multidisciplinary and international perspective on ca…
The Latest Applications For Cellmechanism Research in Drug Discovery Designed to connect research on cell mechanisms with the drug discovery process, Therapeutic Targets: Modulation, Inhibition, and Activation introduces readers to a range of new concepts and novel approaches to drug screening and therapeutic drug targeting to help inform future avenues of drug research. Highly topical, this acces…
Designed to provide a comprehensive but accessible introduction to epilepsy and seizure disorders, Adult Epilepsy provides state-of-the-art information in a concise format useful to a wide audience, from neurology residents to epilepsy fellows and practitioners. This illustrated guide to the assessment, diagnosis, and treatment of epilepsy is a valuable resource enabling clinicians to stay on top …
Schizophrenia is one of the most complex and disabling diseases to affect mankind. Relatively little is known about its nature and its origins, and available treatments are inadequate for most patients. As a result, there are inevitable controversies about what causes it, how to diagnose it, and how best to treat it. However, in the past decade, there has been an explosion of new research, with dr…