The first authoritative overview of past and current strategies for successful drug development by analog generation, this unique resource spans all important drug classes and all major therapeutic fields, including histamine antagonists, ACE inhibitors, beta blockers, opioids, quinolone antibiotics, steroids and anticancer platinum compounds. Of the 19 analog classes presented in detail, 9 are de…
Part of the IUPAC Series on Analytical and Physical Chemistry of Environmental Systems, this book collects and integrates current knowledge of the chemical mechanisms, kinetics, transport and interactions involved in processes at biological interfaces in environmental systems. Provides important, current knowledge for environmental scientists and related fields Highlights key directions for future…
This book aims to stimulate and promote the wide-ranging aspects of green chemistry and its major role in ensuring sustainable development. The book covers the following areas: green chemistry; green reagents and atom economy; safeguarding the atmosphere; industrial green catalysis; alternative reaction conditions; biocatalysis and green chemistry. This book is based on the third edition of the Co…
Жан Чун Ой показывает, как и почему китайская сельская промышленность стала самым быстрорастущим сектором экономики не только в Китае, но и в мире. Ой утверждает, что деколлективизация и децентрализация бюджетной сферы дали партийным чиновникам на местах стимулы выступать в роли предпринимателей и способствовать индустриализации сельской местности во многих районах китайской глубинки. В результате…
Since the days of Diels, Alder and Woodward, cycloadditions have been among the most versatile reactions for stereoselective synthesis … All relevant information is collected in this well-structured, practical handbook. Arranged according to the cycloaddition type, the suitable auxiliaries, reactants, stereoselectivities, yields, and references for each key reaction are compiled in compact tables.…
The only reference to provide both current and thorough coverage of this important analytical technique Static headspace-gas chromatography (HS-GC) is an indispensable technique for analyzing volatile organic compounds, enabling the analyst to assay a variety of sample matrices while avoiding the costly and time-consuming preparation involved with traditional GC. Static Headspace-Gas Chromatograph…
'Spatially Resolved Magnetic Resonance' provides comprehensive and exhaustive coverage of the state of the art in magnetic resonance imaging. Focusing on nonclinical applications, readers learn about the possibilities, limitations and strengths of magnetic resonance methods in a broad range of fields, from materials science, medicine, biology, to geology and ecology. New and innovative application…
As little as a decade ago, radicals were regarded as interesting reactive intermediates with little synthetic use. However, recent results show that radicals have an enormous potential for applications in stereoselective reactions – it's all a matter of knowing what method to use and how to apply it. Three world experts in the field have combined their expertise and present the concepts to underst…
Here, H.-G. Schmalz and T. Wirth have put together a collection of current contributions on the most important topics in organic chemistry all in one handy book. Like its successful predecessors, this volume provides readers with numerous articles on the current state of synthetic methods and their applications. The wide range covered by nearly forty contributions ensures a concise overview of the…
A collection of articles on various topics of organic synthesis – short, precise and topical, written by leading experts in their fields. Organic synthesis is a core subject in organic chemistry, and volumes I and II have been very successful. The topics reflect modern and up-to-date problems and research areas in organic synthesis. Readers will learn about the key synthetic strategies that are im…
The second, completely revised and enlarged edition of what has become the standard reference work in this fascinating field brings together the latest developments, supplemented by numerous practical tips, providing those working in both research and industry with an indispensable source of information. New contributions have been added, to reflect the fact that industrial processes are already e…
An extensive update of the classic reference on organic reactions in water Published almost a decade ago, the first edition has served as the guide for research in this burgeoning field. Due to the cost, safety, efficiency, and environmental friendliness of water as a solvent, there are many new applications in industry and academic laboratories. More than forty percent of this extensively updated…
The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have bee…
The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have bee…
Access state-of-the-art research about trace element contamination and its impact on human health in Trace Elements as Contaminants and Nutrients: Consequences in Ecosystems and Human Health. In this ground-breaking guide, find exhaustive evidence of trace element contamination in the environment with topics like the functions and essentiality of trace metals, bioavailability and uptake biochemist…