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This book gives you an updated and expert overview of nuclear hormone receptors in drug metabolism and drug development and equips you with the interdisciplinary understanding of these receptors and how they can be regulated. Pharmaceutical researchers will find this extremely useful in developing drugs for cancer, heart disease, and diabetes treatment. This comprehensive resource collects scatter…
This book discusses voltage-gated ion channels and their importance in drug discovery and development. The book includes reviews of the channel genome, the physiological bases of targeting ion channels in disease, the unique technologies developed for ion channel drug discovery, and the increasingly important role of ion channel screening in cardiac risk assessment. It provides an important refere…
A comprehensive treatment of model-based fuzzy control systems This volume offers full coverage of the systematic framework for the stability and design of nonlinear fuzzy control systems. Building on the Takagi-Sugeno fuzzy model, authors Tanaka and Wang address a number of important issues in fuzzy control systems, including stability analysis, systematic design procedures, incorporation of perf…
This book introduces the finite element method applied to the resolution of industrial heat transfer problems. Starting from steady conduction, the method is gradually extended to transient regimes, to traditional non-linearities, and to convective phenomena. Coupled problems involving heat transfer are then presented. Three types of couplings are discussed: coupling through boundary conditions (s…
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
An essential resource for graduate students, academic and industrial toxicologists, and environmental health scientists and professionals Over the course of thirty years and three editions, Introduction to Biochemical Toxicology has been an important source for coverage of the ongoing quest to define the biochemical, cellular, and molecular events induced by toxicants at the cellular and organismi…
Discover the link between the latest chemical biology approaches and novel drug therapies! Protein Targeting with Small Molecules: Chemical Biology Techniques and Applications takes readers beyond the use of chemical biology in basic research, providing a highly relevant look at techniques that can address the challenges of biology and drug design and development. This indispensable bench companio…
Nature provides us with an abundance of chemical potential. Presenting an overview of the use of bioresources in the 21st century, Introduction to Chemicals from Biomass covers resources, chemical composition of biomass, key factors affecting composition, utilization of wastes, extraction technologies, controlled pyrolysis, fermentation, platform molecules, and green chemical technologies for thei…
This extensively updated and revised version builds on the success of the first edition featuring new discoveries in powder technology, spraying techniques, new coatings applications and testing techniques for coatings – Many new spray techniques are considered that did not exist when the first edition was published! The book begins with coverage of materials used, pre-spray treatment, and the tec…
At a time when environmental concerns are increasing, it's important that chemical processes are as environmentally friendly as possible. This book outlines various methods for producing inorganic and organic solvents without the use of traditional solvents that can have detrimental effects on the environment. This is the first book to give extensive and exclusive coverage to the topic Includes im…
A guide to achieving business successes through statistical methods Statistical methods are a key ingredient in providing data-based guidance to research and development as well as to manufacturing. Understanding the concepts and specific steps involved in each statistical method is critical for achieving consistent and on-target performance. Written by a recognized educator in the field, Statisti…
Random signals and noise are present in many engineering systems and networks. Signal processing techniques allow engineers to distinguish between useful signals in audio, video or communication equipment, and interference, which disturbs the desired signal. With a strong mathematical grounding, this text provides a clear introduction to the fundamentals of stochastic processes and their practical…
Semiconductor-based Ultra-Fast All-Optical Signal Processing Devices –a key technology for the next generation of ultrahigh bandwidth optical communication systems! The introduction of ultra-fast communication systems based on all-optical signal processing is considered to be one of the most promising ways to handle the rapidly increasing global communication traffic. Such systems will enable real…
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
The first edition of this title has become a well-known reference book on ion sources. The field is evolving constantly and rapidly, calling for a new, up-to-date version of the book. In the second edition of this significant title, editor Ian Brown, himself an authority in the field, compiles yet again articles written by renowned experts covering various aspects of ion source physics and technol…