Until now colloid science books have either been theoretical, or focused on specific types of dispersion, or on specific applications. This then is the first book to provide an integrated introduction to the nature, formation and occurrence, stability, propagation, and uses of the most common types of colloidal dispersion in the process-related industries. The primary focus is on the applications …
Divided into the three main sections of synthesis, analysis and drug development, this handbook covers all stages of the drug development process, including large-scale synthesis and purification of chirally pure pharmaceuticals. The two editors from academia and a major pharmaceutical company have assembled an experienced, international team who provide first-hand practical advice and report prev…
This handbook is the first to address the practical aspects of this novel method. It provides a complete overview of the field and progresses from general considerations to real life scenarios in drug discovery research. Starting with an introductory historical overview, the authors move on to discuss ligand-based approaches, including 3D pharmacophores and 4D QSAR, as well as the concept and appl…
This book builds up on the success of the first edition of Paints, Coatings, and Solvents. The first edition has been completely revised, the second edition thus is an up-to-date overview of the industrial aspects of paints, coatings, and solvents including composition, production, processing, uses, and methods of analysis. Special attention is given to toxicology and environmental protection matt…
Most drugs bind to a clearly defined macromolecular target that is complementary in terms of structure and chemistry. This observation is the basic paradigm of structure-based ligand design. Although this method first emerged in the 1980s, it has already become a powerful tool for pharmaceutical research. Much has been learned, however, since the first attempts to discover drugs on the basis of av…
Adhesion is among the oldest technologies known to mankind, but the technology of adhesives began to boom with the developments in chemistry in the early 1900s. The last few years have seen tremendous progress in the performance of adhesives, allowing two pieces to be connected inseparably. Modern adhesives perform so well that more sophisticated joining methods, e.g. welding, can often be replace…
Quantitative studies on structure-activity and structure-property relationships are powerful tools in directed drug research. In recent years, various strategies have been developed to characterize and classify structural patterns by means of molecular descriptors. It has become possible not only to assess diversities or similarities of structure databases, but molecular descriptors also facilitat…
Microcomponents and microdevices are increasingly finding application in everyday life. The specific functions of all modern microdevices depend strongly on the selection and combination of the materials used in their construction, i.e., the chemical and physical solid-state properties of these materials, and their treatment. The precise patterning of various materials, which is normally performed…
The ability of condensation polymers to undergo additional chemical reactions, so-called transreactions, is really fascinating. These processes lead to novel copolymers with desired composition and sequential order, allow to enhance the compatibility and to minimize molecular weight fluctuations during polycondensation and processing and to provide for chemical healing of laminates of condensation…
Dynamic environmental processes are complex; the easiest and most effective way to understanding them lies through the disciplines of dynamic modelling and computer simulation. The prerequisite modelling fundamentals are presented in the first chapter in a manner comprehensible to students as well as to practising scientists and engineers. The second chapter describes the many environmental proces…
Dedicated wholly to automotive coatings, this book is the first of its kind. It provides an in-depth coverage of the subject and in keeping with the international nature of the automotive business the book has a truly multinational flavour with authors selected from Australia, Japan, Europe and the USA. An authoritative and informative treatment of all aspects of coatings formulation are presented…
Now in its second edition and still the only book of its kind, this is an authoritative treatment of all stages of the coating process – from body materials, paint shop design, and pre-treatment, through primer surfacers and top coats. New topics of interest covered are color control, specification and testing of coatings, as well as quality and supply concepts, while valuable information on capit…
This beautiful compilation of invited review articles – authored by well-known scientists – covers the latest developments and achievements in colloid and interface science, and is dedicated to Professor Tharwat Tadros, an outstanding scientist in the field. Due to the fact that colloid science involves a great number of disciplines, the papers discuss such hot topics as emulsions, nano-particles,…
This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from microbes to man, it begins with a look at human and mammalian transporters. This is followed by microbial, fungal and parasitic transporters with special att…
With this valuable practical guide, three members of the Harvard Stem Cell Institute have compiled and edited the definite handbook for the exciting new field of human embryonic stem cell research. The editors have gathered protocols from scientists with extensive reputation and expertise, describing and comparing currently used techniques for the culture of human stem cells and discussing the str…