Gramicidin channels have been studied intensively for more than 25 years. They serve as model transport systems for large protein ion channels, since it is difficult to glean high-resolution structural information on the latter. This book includes contributions from virtually all the major scientists studying gramicidin channels and is the only compilation of work in this field. It discusses crystallographic, spectroscopic, electrophysiological and computational studies, especially in the light of the recent availability of high-resolution structural data, and it compares these with insights derived from larger systems. As well as drawing together much new and exciting work in this field, it provides pointers to promising new research directions.

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Gramicidin and Related Ion Channel-Forming Peptides

The Origins and Consequences of Obesity

Oligonucleotides as Therapeutic Agents

Characterizing Human Psychological Adaptations

Telomeres and Telomerase

Bacterial Responses to pH

Gap Junction-Mediated Intercellular Signalling in Health and Disease

Variation in the Human Genome

Olfaction in Mosquito-Host Interactions