Книги жанра медицина
Stereological methods provide researchers with unparalleled quantitative data from tissue samples and allow for well-evidenced research advances in a broad range of scientific fields. Presenting a concise introduction to the methodology and application of stereological research in neuroscience, Neurostereology provides a fuller understanding of the use of these methods in research and a means for …
Explains how to perform and analyze the results of the latest physicochemical methods With this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and their effects on drug absorption. The book emphasizes oral absorption, explaining all the physicochemical methods used today to ana…
Chronopharmaceutics Science and Technology for Biological Rhythm Guided Therapy and Prevention of Diseases Edited by Bi-Botti C. Youan The first standard reference on chronopharmaceutics As we better understand how biological processes unfold in real time through advances in chronobiology and related fields, we can create safer, more effective drugs, drug delivery systems, and disease monitoring a…
Since publication of the first edition, huge developments have taken place in sensory biology research and new insights have been provided in particular by molecular biology. These show the similarities in the molecular architecture and in the physiology of sensory cells across species and across sensory modality and often indicate a common ancestry dating back over half a billion years. Biology o…
Discover new and emerging applications for microdialysis in drug evaluation Microdialysis is a highly valuable sampling tool that can be used in vivo to measure free, unbound analyte concentrations located in interstitial and extracellular spaces. This book explores the full range of clinical applications for microdialysis, focusing on its use in different organ and tissue systems for pharmacokine…
The focus of early drug development has been the submission of an Investigational New Drug application to regulatory agencies. Early Drug Development: Strategies and Routes to First-in-Human Trials guides drug development organizations in preparing and submitting an Investigational New Drug (IND) application. By explaining the nuts and bolts of preclinical development activities and their interpla…
Profiles potential treatment approaches for cardiac arrhythmias Cardiac arrhythmias of ventricular origin are responsible for the deaths of nearly half a million Americans each year while atrial fibrillation accounts for about 2.3 million cases per year, a rate that is projected to increase 2.5 fold over the next half century. Effectively managing these cardiac rhythm disorders remains a major cha…
A comprehensive look at current drug discovery and development methods—and the roadmap for the future Providing both understanding and guidance in characterizing potential drugs and their production and synthesis, Development of Therapeutic Agents Handbook gives professionals a basic tool to facilitate research and development within this challenging process. This comprehensive text brings togethe…
Cosmesis of the Mouth, Face and Jaws provides a unique, whole-face approach to cosmetic procedures, focusing on oral, facial and gnathic components. Covering the core repertoire of cosmetic facial and dental procedures, including oral and maxillofacial surgery, cosmetic dentistry, prosthetic dentistry, orthodontics, head and neck surgery, plastic surgery, dermatology and more, this landmark text o…
The definitive book on the neutralization of recombinant biopharmaceuticals Recombinant biopharmaceuticals are an important tool for treating a range of illnesses; however, their efficacy can be severely impaired by their immunogenicity. When introduced into the body, these pharmaceuticals can cause the immune system to produce anti-drug antibodies (ADAs) that neutralize their effects. The first a…
This second edition of Principles and Practice of Travel Medicine has been extensively updated to provide a comprehensive description of travel medicine and is an invaluable reference resource to support the clinical practice of travel medicine. This new edition covers the many recent advances in the field, including the development of new and combined vaccines; malaria prophylaxis; emerging new i…
Small Animal Soft Tissue Surgery is a comprehensive, in-depth resource for well-referenced, current information on small animal soft tissue surgery. Offering detailed surgical techniques in a well-illustrated, easy-to-follow format, the book covers the full range of surgically treated diseases and syndromes, with video clips and slideshows to demonstrate surgical procedures on an accompanying DVD.…
This book examines genotoxic impurities and their impact on the pharmaceutical industry. Specific sections examine this from both a toxicological and analytical perspective. Within these sections, the book defines appropriate strategies to both assess and ultimately control genotoxic impurities, thus aiding the reader to develop effective control measures. An opening section covers the development…
How do you identify which neurological syndromes occur due to systemic disease? Neurological problems commonly occur in the context of underlying systemic disease, and may even be the presenting symptom of a medical condition that has not yet been diagnosed. Consequently neurologists need to be aware when a neurological presentation might indicate an underlying systemic disorder. Neurologic Disord…
Offering patients a higher safety profile and less discomfort than radio-frequency ablation, catheter cryoablation is a safe, effective and efficient alternative for clinicians treating atrial fibrillation and other arrhythmias. In The Practice of Catheter Cryoablation for Cardiac Arrhythmias, cardiac electrophysiologists, cardiologists and cardiology fellows will be able to gain an in-depth updat…