Most drugs bind to a clearly defined macromolecular target that is complementary in terms of structure and chemistry. This observation is the basic paradigm of structure-based ligand design. Although this method first emerged in the 1980s, it has already become a powerful tool for pharmaceutical research. Much has been learned, however, since the first attempts to discover drugs on the basis of av…
Adhesion is among the oldest technologies known to mankind, but the technology of adhesives began to boom with the developments in chemistry in the early 1900s. The last few years have seen tremendous progress in the performance of adhesives, allowing two pieces to be connected inseparably. Modern adhesives perform so well that more sophisticated joining methods, e.g. welding, can often be replace…
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Plant Breeding Reviews presents state-of-the-art reviews on plant breeding and genetics covering horticultural, agronomic and forestry crops, incorporating both traditional and molecular methods. The contributions are authored by world authorities, anonymously reviewed, and edited by Professor Jules Janick of Purdue University, USA. The series is an indispensible resource for crop breeders, plant …
Plant Breeding Reviews presents state-of-the-art reviews on plant breeding and genetics covering horticultural, agronomic and forestry crops, incorporating both traditional and molecular methods. The contributions are authored by world authorities, anonymously reviewed, and edited by Professor Jules Janick of Purdue University, USA. The series is an indispensible resource for crop breeders, plant …
Absorption and Scattering of Light by Small Particles Treating absorption and scattering in equal measure, this self-contained, interdisciplinary study examines and illustrates how small particles absorb and scatter light. The authors emphasize that any discussion of the optical behavior of small particles is inseparable from a full understanding of the optical behavior of the parent material-bulk…
Written by a distinguished plasma scientist and experienced author, this up-to-date work comprehensively covers current methods and new developments and techniques, including non-equilibrium atomic and molecular plasma states, as well as such new applications as gas lasers. Containing numerous appendices with reference data indispensable for plasma spectroscopy, such as statistical weights and par…
The applications of electromagnetic phenomena within electrical engineering have been evolving and progressing at a fast pace. In contrast, the underlying principles have been stable for a long time and are not expected to undergo any changes. It is these electromagnetic field fundamentals that are the subject of discussion in this book with an emphasis on basic principles, concepts and governing …
Applied Electromagnetics and Electromagnetic Compatibility deals with Radio Frequency Interference (RFI), which is the reception of undesired radio signals originating from digital electronics and electronic equipment. With today's rapid development of radio communication, these undesired signals as well as signals due to natural phenomena such as lightning, sparking, and others are becoming incre…
This is the first comprehensive monograph that features state-of-the-art multigrid methods for enhancing the modeling versatility, numerical robustness, and computational efficiency of one of the most popular classes of numerical electromagnetic field modeling methods: the method of finite elements. The focus of the publication is the development of robust preconditioners for the iterative solutio…
Based on a fifty-year study conducted by the Leibniz Institute for Baltic Sea Research, this book brings together a comprehensive summary of their observations and findings. Written by well-known experts, this revealing book concentrates on long-term changes in the Baltic Sea?which can be extrapolated to shed light on the environmental problems of other shelf seas, brackish seas, and large estuari…
Economics, Ethics, and Environmental Policy: Contested Choices offers a comprehensive analysis of the ethical problems associated with basing environmental policy on economic analysis, and ways to overcome these problems.
The growth of the environmental sciences has greatly expanded the scope of biological disciplines today's engineers have to deal with. Yet, despite its fundamental importance, the full breadth of biology has been given short shrift in most environmental engineering and science courses. Filling this gap in the professional literature, Environmental Biology for Engineers and Scientists introduces st…
The mapping of human genes is proceeding rapidly. Genes associated with specific inherited diseases are being identified, often providing insight into the molecular cause of the disease. At the moment, however, little consideration is being given to the variation present in different human populations. Variation in the Human Genome discusses methods of analysing population genetic data and how con…
The mapping of human genes is proceeding rapidly. Genes associated with specific inherited diseases are being identified, often providing insight into the molecular cause of the disease. At the moment, however, little consideration is being given to the variation present in different human populations. Variation in the Human Genome discusses methods of analysing population genetic data and how con…