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This completely revised and updated fourth edition of the best-selling classic is a thorough treatment of the subject while remaining concise and readable. New additions include capillary electrophoresis, monolithic columns, zwitterion colums, DNA/RNA analysis, fundamentals of the science of IC, and micro methods. The whole is rounded off by handy tables with details on detection or elution condit…
Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for correct data evaluation. Chapter authors from leading pharmaceutical companies as well as from Harvard University discuss such factors as chemical genetics, binding, cell-based and biochemical assays, the effici…
A valuable presentation of theoretical and practical information in the area of liquid-solid filtration. The development of theoretical models is highlighted with practical design data and problem-related examples. Modern trends, e.g., membrane systems, are reported together with the fundamental aspects of particulate technology. The increasing interest in pollution control and environmental prote…
'Spatially Resolved Magnetic Resonance' provides comprehensive and exhaustive coverage of the state of the art in magnetic resonance imaging. Focusing on nonclinical applications, readers learn about the possibilities, limitations and strengths of magnetic resonance methods in a broad range of fields, from materials science, medicine, biology, to geology and ecology. New and innovative application…
Since the book first appeared in 1976, Methods of Seawater Analysis has found widespread acceptance as a reliable and detailed source of information. Its second extended and revised edition published in 1983 reflected the rapid pace of instrumental and methodological evolution in the preceding years. The development has lost nothing of its momentum, and many methods and procedures still suffering …
Teaches and enables students to build confidence in drawing and manipulating curly arrows, a fundamental skill for all organic chemists This book is an interactive approach to learning about chemistry of the carbonyl group—inviting students to work through its pages with pencil and paper in hand. It educates with the belief that the most effective way to learn is by practice and interaction. With …
The first comprehensive coverage of all facets of the Claisen rearrangement and its variants. As such, this book helps synthetic chemists to exploit the vast potential of this elegant C-C linking reaction, discusses a wealth of catalytic options, and gives those more theory-minded chemists a detailed insight into the mechanistic aspects of the Claisen rearrangement. An invaluable source of informa…
A comprehensive resource to the development and recent progress of zwitterion-oriented cycloadditions promoted by organoamines, organophosphines, N-heterocyclic carbenes Organocatalytic Cycloadditions for Synthesis of Carbo- and Heterocycles offers a clear explanationto thedevelopment of and the information on the latest research pertaining to zwitterion-oriented cycloadditions promoted by organoa…
An up-to-date account of this cutting-edge research in a consistent and understandable framework, of special interest to experts in other areas of electronic structure and/or quantum many-body theory. It will serve equally well as a self-contained guide to learning about reduced density matrices either through self-study or in a classroom as well as an invaluable resource for understanding the cri…
Based on a symposium on lasers, molecules, and methods held at the Los Alamos Center for Nonlinear Studies held in July 1986. Contributors present recent advances in theoretical and experimental research on a diversity of dynamical and optical phenomena resulting from the interactions of laser beams with molecules. They describe the predictive results of sophisticated mathematical models, the equi…
In keeping with the outstanding importance of lipophilicity in biosciences, this volume examines all its facets in more than twenty contributions from leading experts. It offers a thorough and highly topical survey of this rapidly developing field of research. Color plates demonstrating structural aspects, a vast number of references, and the straightforward presentation of the material make this …
Sustainable development is now accepted as a necessary goal for achieving societal, economic and environmental objectives. Within this chemistry has a vital role to play. The chemical industry is successful but traditionally success has come at a heavy cost to the environment. The challenge for chemists and others is to develop new products, processes and services that achieve societal, economic a…
This book describes the new imaging techniques being developed to monitor physiological, cellular and subcellular function within living animals. This exciting field of imaging science brings together physics, chemistry, engineering, biology and medicine to yield powerful and versatile imaging approaches. By combining advanced non-invasive imaging technologies with new mechanisms for visualizing b…
An international group of leading investigators discuss recent progress of sensory structures in lower and higher vertebrates. Experts in two relevant fields–the cell cycle and mitogenic growth factors–present insightful contributions in the search for precursors and/or stem cells in each sense organ plus the signals which regulate those precursors' differentiation both in normal development and r…